List of Aromatase inhibitors
Combinations of the new aromatase inhibitors with LHRH agonists are therefore now being prospectively studied. British investigators have made a preliminary report of their study of premenopausal women who received anastrozole with goserelin for locally advanced or metastatic breast cancer. Eight of nine evaluable patients were progression-free after 6 months of treatment.64 The ABCSG is conducting an adjuvant study of goserelin plus anastrozole vs goserelin plus tamoxifen (ABCSG Study 12).
With the chemical formula name Androsta-3,5-diene-7,17-dione, more simply known as Arimistane, this is another aromatase inhibitor (AI) I’ll be looking at. This is a unique AI because you might have seen it as an ingredient in over-the-counter supplements that operate in a gray legal area, especially those designed specifically for PCT use. Like all steroids, it blocks the HPTA axis, so PCT is necessary after the cycle is completed.
- The best estrogen blocker and testosterone booster on the market in our opinion is Testogen.
- These products contain different ingredients, which prevents your body from adapting to them.
- Control your diet and your carbohydrate intake and you will do a lot for controlling water retention.
Most of the time, I’ll stick to Clomid combined with an AI such as Arimidex. I would consider using Nolvadex and an aromatase inhibitor, depending on how much you’ve used and how long the cycle was. Still, it is not legal to use in sporting competitions or professional sports of any kind because it is listed as a prohibited performance-enhancing substance. The main reason for this is that as an aromatase inhibitor, it lowers estrogen levels, so theoretically, it can help with muscle gain.
Aromasin vs. Letrozole
One recommended dosage is 40mg daily in the first week, 20mg daily for the next two weeks, and 10mg daily for the fourth and final week. In a 3-week protocol, one of the recommended dosages is to take 100mg on the first day, followed by 60mg for 10 days, then drop to 40mg for the final 10 days. Keep in mind that Nolvadex is not useful for mitigating other types of estrogenic side effects besides gynecomastia. If longer-term use is required (2-3 months) to reverse more https://clocktowerscafe.co.uk/proviron-an-insight-into-its-benefits-and-uses/ advanced gyno, Raloxifene is known to be safe for use over this period.
Availability of Nandrolone
In certain breast cancers, estrogen fuels the growth of cancer cells. Aromasin, as an aromatase inhibitor, is used to decrease the amount of estrogen in the body, thereby halting the growth or return of breast cancer. Exemestane is an orally taken aromatase inhibitor, which is also known as Aromasin. Manufactured by Natco Pharma, users combine XTANE with a cycle of anabolic steroids. This acts as an aromatase inhibitor, which prevents some of the detrimental side effects that can occur while enhancing the effects of the steroid cycle.
It is often confused with regular DHEA, which leads to Arimistane being compared to or even confused with DHEA, so athletes must be aware that these are all different compounds. Arimistane is an aromatase inhibitor drug with powerful anti-estrogen effects. This is one of the few AIs that is legal without a prescription and can even be bought over the counter in some locations. Despite this, Arimistane is still a prohibited substance by the World Anti-Doping Agency (WADA) but was only put on the banned list in 2017. Exemestane is being studied in BIG (also known as Study 96 OEXE 031-C/13/96), coordinated by the British-based International Collaboration Cancer Group (ICCG).
However, if you try Minoxidil, use it alongside RU or Finasteride because it will not prevent hair loss. Your only option for hair loss prevention will be RU-58841, as Finasteride will have no impact. While it poses zero harm to your physical health, thinning or hair loss on your head can zap your self-esteem when you’re a young guy.
Because it’s a very potent AI, you only need low doses of Letrozole to get its full benefits while minimizing side effect risks. Sometimes, you might only want to take it for a week to eliminate early signs of gyno. Doses of 1.25 to 2.5 daily are more than sufficient to mitigate estrogenic side effects on the cycle. To run a PCT cycle using Letrozole, look at my in-depth Letrozole PCT guide. When you use Arimidex on a cycle, you can take it every 2-3 days because of its longer half-life, and it’s very effective at preventing testosterone conversion to estrogen. Like all AIs, you need to make sure you don’t dose it too high, or your estrogen levels can crash too low.
The Cyclosome™ approach can be useful in increasing prohormone solubility and vesicles stability, in controlling the in vivo fate of hydrophobic compounds and in avoiding burst release of prohormones from the vesicles. To obtain a stable Cyclosome™, the CDs should have a higher affinity to prohormone molecules compared with liposomal membrane lipids. These products contain different ingredients, which prevents your body from adapting to them. What’s important, however, is that the products you cycle overlap minimally in ingredients.
Many women will be required to take Arimidex for up to five years to help control the growth of cancerous tumors. This long-term administration of Arimidex comes with an increased risk of side effects that we rarely or never see with the short-term use that steroid users undertake with this drug. But even more severe is the issue of high blood pressure that can result from excess water retention – increasing the risk of stroke or heart attack. Controlling water retention as much as possible is vital for your results and health. Arimidex, with its anti-estrogen functionality, provides an essential tool for steroid-using bodybuilders to prevent or at least greatly minimize water retention during a steroid cycle. Keep in mind that for most guys, Arimidex will not be strong enough as a testosterone stimulator to use alone in post-cycle therapy, and some choose not to use it at all.
